| Autor: |
Caglayan, Kasim, Erdogan, Nilsen, Avci, Bahattin, Gungor, Bulent, Cinar, Hamza, Arslan, Nilden |
| Přispěvatelé: |
Ondokuz Mayıs Üniversitesi |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
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| Popis: |
AVCI, Bahattin/0000-0001-6471-6495; WOS: 000322208300003 PubMed: 23709371 Objectives. The authors aimed to investigate the effect of a-Glucan on healing of an experimental left-sided colon anastomosis model. Material and Methods. Twenty adult male Wistar albino rats were randomized into two groups which had colonic transection and end-to-end anastomosis. Group I (Control): anastomosis group, received no treatment (n = 10); group II, anastomosis + beta-Glucan (50 mg/kg/day within seven days after surgical procedure). Bursting pressure, hydroxyproline levels and histopathological characteristics of the anastomosis were analyzed. Results. The average burst pressure of Groups land II were 106.67 +/- 5.00 and 148.00 +/- 11.35 mm Hg and hydroxyproline levels were 0.85 +/- 0.14 and 1.45 +/- 0.46 mu g/mg, respectively. Both the burst pressure and hydroxyproline levels in group II were statistically significantly higher (p < 0.05). Histopathological examination revealed less epithelial damage in group II (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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