| Autor: |
Yüce Ö., Kalayci A.G., Okuyucu A., Caltepe G., Bedir A. |
| Přispěvatelé: |
Ondokuz Mayıs Üniversitesi |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Popis: |
Objective: To investigate the presence of genotoxicity in intestinal epithelial cells and lymphocytes in celiac patients and to assess DNA repair capacity. Material and Method: The study comprised 15 newly diagnosed celiac patients, 14 celiac patients receiving glutenfree diet, and 9 non-celiac patients who had undergone endoscopy for various reasons (control group). Comet assay was performed to detect DNA injury. DNA injury was measured both after being exposed to stress by hydrogen peroxide and 20 minute regeneration period to measure DNA repair capacity. Results: DNA injury in the intestinal epithelial cells was significantly higher in the newly diagnosed celiac patients than that in the controls (Tail DNA%: 25.9±1.5 and 15.7±0.9, respectively, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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