| Autor: |
Yazıcı, Tarkan, Bahçeci, İlkay, Uçucu, Süheyl, Bahçeci, Bülent |
| Přispěvatelé: |
RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Bahçeci, İlkay, Bahçeci, Bülent |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Popis: |
Aim: The aim of the study is to investigate the relationship between depression and changes in 25-OH Vitamin D and Lipoprotein serum levels, which have been suggested to be associated with Central Nervous System neurotransmission and certain psychiatric disorders. Material and Methods: The study included a patient group consists of 40 depressive individuals who have applied to the Psychiatry outpatient clink of our hospital and have been first diagnosed with depression according to SCID-1 (Structured Clinical Interview for DSM IV Axis I Disorders) criteria and had no psychiatric or systemic disease that could affect the result, as well as a control group of 40 healthy individuals with similar demographic characteristics. In the collected serum samples. 25-OH vitamin D, LDL, HDL, VLDL, total cholesterol, and TG levels were measured enzymatically and spectrophotometrically: Apolipoprotein Al and Bl00 levels were measured nephelometrically, LDL and HDL subfractions were measured using the Upoprint System, and then the results were evaluated statistically. Results: Atherogenic LDL 3 and LDL 4 were significantly higher In the patient group (p=0.001 and p=0.0155, respectively). The mean LDL particle diameter (LDL Mean) was significantly lower in the patient group (13-0.0017). There was no significant difference between the patient and control groups in terms of Buoyant LDL, but Small Dense LDL levels were significantly higher in the patient group (p=0.008 and p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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