| Autor: |
Nursoy, M., Kahraman, F. U., Gedik, A. H., Kocyigit, A., Cakir, F. B., Cakir, E., Kiyak, M. C. |
| Přispěvatelé: |
ÇAKIR, Erkan |
| Rok vydání: |
2022 |
| Předmět: |
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| Popis: |
Background: The aim of this study was to measure the serum levels of myeloperoxidase (MPO), paraoxonase (PON1) and arylesterase (ARE) in paediatric patients with non-cystic fibrosis bronchiectasis (non-CF BE), and to compare these results with healthy controls. Methods: A total of 101 paediatric patients with non-CF BE and 70 age- and sex-matched healthy controls were enrolled into the study between November 2010 and November 2015. The levels of MPO, PON1 and ARE were measured in all participants. Findings: Compared to controls, MPO levels were significantly lower (p=0.001), while PONI and ARE levels were significantly higher in the patient group (p=0.001). Conclusion: Our study reports that the oxidant and anti-oxidant enzyme levels in non-CF BE differ from healthy controls; thus, suggesting a role in non-CF BE pathophysiology. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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