A study of surface water pollution with azithromycin in Ukraine

Autor:	Yeromina, Hanna, National University of Pharmacy, Ieromina, Zinaida, Fedosov, Andrii, Vislous, Olha, Suleiman, Мarharyta, Upyr, Taras, Sych, Irina, Perekhoda, Lina
Rok vydání:	2022
Předmět:	pollutants antibiotic resistance thin-layer chromatography surface water PEC PNEC EMA
Zdroj:	Scripta Scientifica Pharmaceutica; Vol 9, No 1 (2022); 29-34
ISSN:	2367-5500 2367-6000
Popis:	Introduction: Water pollution with antibiotics plays a key role in the formation and spread of antibiotic resistance, which threatens humanity and the environment as a whole.Aim: The purpose of our work was to develop a method for determining azithromycin in wastewater and surface water using the thin-layer chromatography method.Materials and Methods: The developed technique was tested in the wastewater of Zolochiv district of Kharkiv region.Results and Discussion: Using conventional analytical scales and universal chromatography in thin layers of a sorbent, it is possible to identify azithromycin with a water concentration of ≥ 30 µg/mL without complex and expensive equipment, such as HPLC or LC/MS/MS. The results showed that the concentration of azithromycin is less than 30 µg/mL.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______9626::f150b5fb9b6cf43e2bf198ed75c32d4d https://journals.mu-varna.bg/index.php/ssp/article/view/8586 Zobrazit plný text záznamu