| Autor: |
Aleksandrov, Lyubomir, Rangelova, Nadezhda, Angelova, Tsvetelina, Georgieva, Nelly |
| Rok vydání: |
2021 |
| Předmět: |
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| Popis: |
In this study SiO2/hydroxypropyl cellulose matrix doped with different amount copper ions was obtained by sol-gel route. The synthesized composites were tested as antimicrobial agents. The SiO2 was derived from tetraethyl orthosilicate. The carbohydrate content in all samples was 5 wt.%, and the amount of Cu(NO3)2*3H2O added as a source of Cu ions was varied from 0 to 5 wt.%. The principles of the composites formation were developed using structural data from Fourier transform infrared spectroscopy (FT-IR) and Differential thermal analysis (DTA/TG). Based on the structural studies was shown that the interaction between silica and the cellulose ether it occurs by formation of H-bonds. By optical microscopy it was found that in all sample copper ions are homogenous dispersed in the amorphous matrix. Using optical absorption spectra (UV-Vis) the bang gap energy was determined. The final stage of this investigation was to test the antimicrobial activity of materials against to model strains of Gram + (Bacillus subtilis 3562) and Gram - (Escherichia coli K12) bacteria and the model strain fungi (Candida albicans 74). The studies have shown that the highest sensitivity to the test materials, with the formation of the greatest inhibitions zones is observed by B. subtilis and C. albicans. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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