Determination of 3D printed blood vessel replica that reproduces physiological diameters during cardiac cycle

Autor: Letica, Ivan Krešimir
Přispěvatelé: Karšaj, Igor
Jazyk: chorvatština
Rok vydání: 2023
Předmět:
Popis: Aditivna proizvodnja (3D printanje) dobiva sve veći značaj u medicinskoj industriji. Osim u proizvodnji umjetnih tkiva, njena primjena je vidljiva i u raznim istraživanjima u području zdravstvenog razvoja. Cilj ovog rada je dobivanje modela neopterećene geometrije krvnih žila, aorta, s aneurizmom. Ti modeli namijenjeni su za proizvodnju 3D printanjem uporabom hiperelastičnih materijala. Oni su dobiveni numeričkom metodom koja se temelji na mehanici kontinuuma. U toj se metodi uzimaju medicinski podaci o geometriji opterećenih krvnih žila kod ljudi te se iterativnim proračunom dolazi do geometrije neopterećenih krvnih žila. U radu su izvedeni i zapisani izrazi korišteni u numeričkoj metodi te je opisano na koji način se ona provodi. Njom su dobiveni modeli aorti s aneurizmom od jednog i više hiperelastičnih materijala. Modeli su analizirani metodom konačnih elemenata te je njihova opterećena geometrija uspoređena s geometrijom stvarnih ljudskih žila s aneurizmom. Additive manufacturing (3D printing) is gaining more and more importance in the medical industry. In addition to the production of artificial tissues, its application is also visible in various research in the field of health development. The aim of this paper is to obtain models of the unloaded geometry of blood vessels, aorta, with an aneurysm. These models are intended for production by 3D printing using hyperelastic materials. They were obtained by a numerical method based on continuum mechanics. In this method, medical data on the geometry of human loaded blood vessels are taken, and the geometry of unloaded blood vessels is arrived at by an iterative calculation. In the paper, the expressions used in the numerical method are derived and written down, and the way in which they are implemented is described. It was used to obtain models of aorta with aneurysm made out from one or more hyperelastic materials. The models were analyzed using the finite element method and their loaded geometry was compared with the geometry of real human blood vessels with aneurysm.
Databáze: OpenAIRE