| Autor: |
Taştekin, Bora, Öcal, Işıl, Yılmaz, M. Bertan, Öksüz, Hale, Özpak, Lütfiye, Günay, İsmail |
| Přispěvatelé: |
Çukurova Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Taştekin, Bora, Öcal, Işıl, Yılmaz, M. Bertan, Öksüz, Hale, Özpak, Lütfiye, Günay, İsmail |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Introduction: The purpose of this study is to examine whether acute or chronic y exposure to 50 Hz frequency pulsed magnetic field (PMF) has adverse effects on contraction proteins and parameters of the uterine muscle in pregnancy terms of rats. Methods: Pregnant fifty-six rats were divided into 8 groups (in each group, n= 7) according to pregnancy terms of rats as: Exposed-pulsed magnetic field (Control, Early-PMF, Middle-PMF and Late-PMF of pregnancy terms) and unexposed groups. At the end of the pregnancy terms of rats, blood samples were collected blood to measure the levels of myosin light chain kinase (MYLK) and calmodulin (CAM)), then, uterine rings were mounted in an organ bath. Uterine rings were allowed to equilibrate at 1.5 g tension for 60 min. The amplitude of contraction-force and contractionfrequency in uterine rings were measured with isometric force transducers and MP35 systems. Results: The uterine contraction force and contraction frequency were analyzed as gram-force and contraction frequency (per 5-minute (frequency). At early and late terms of pregnancy, contraction force and frequency decreased in the groups exposed to pulsed magnetic field when compared to the control groups. Myosin light chain kinase (MYLK) and calmodulin (CAM) levels of early and late pregnancy terms of rats in exposed to pulsed magnetic field groups were found to decrease significantly compared to control groups. Conclusion: Our findings suggest that acute or chronically non-invasive pulsed magnetic field exposure have no adverse effects in terms of pregnancy if the mother does not have any other symptomatic problem. Therefore, there is a need for more detailed investigations to conclude the effects of acute or chronic exposure to pulsed magnetic field. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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