The Investigation of Plasma Glucagon-like Peptide-1 Levels in Newly Diagnosed Type 1 Diabetic Children

Autor: Uslu, B., Gurbuz, F., Temiz, F., Yuksel, B., Mungan, N., Topaloglu, A. K.
Přispěvatelé: Çukurova Üniversitesi
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Popis: WOS: 000393480700023 PubMed ID: 26901603 Objective: To reveal the possible role of glucagon-like peptide-1 (GLP-1) in newly diagnosed Type 1 diabetic children. Methods: Twenty-five newly diagnosed children and 22 healthy children were included in the study. Results: In oral glucose tolerance tests, no correlation was observed between C-peptide and GLP-1 levels at 0 and 30 minutes, and plasma GLP-1 levels in both groups at 0 and 30 minutes were not statistically different. Conclusion: Consequently, fasting and postprandial GLP-1 levels in newly diagnosed Type 1 diabetic children are not different from healthy children. Glucagon-like peptide-1 levels in newly diagnosed Type 1 diabetic children suggest that plasma GLP-1 levels do not have any role in the pathogenesis of Type 1 diabetes mellitus.
Databáze: OpenAIRE