Popis: |
We treated two patients with SSPE by using intramuscular interferon beta (IFN-ß) and oral isoprinosine for 5 and 6 months. However, we found no effect on the clinical course, magnetic resonance findings and measles antibody titers of the cerebrospinal fluid. The different responses to the therapy may be explained by the changes of virus subtypes responsible in recent years or the differences of the immunity capabilities of the hosts. Further multicenter collaborative controlled studies are needed to determine the efficacy of (IFN-ß). |