| Autor: |
Öcal, Işıl, Taştekin, Bora, Çoban, Fatma, Yılmaz, M. Bertan, Öksüz, Hale, Günay, İsmail |
| Přispěvatelé: |
Çukurova Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Öcal, Işıl, Taştekin, Bora, Çoban, Fatma, Yılmaz, M. Bertan, Öksüz, Hale, Günay, İsmail |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
The purpose of this study is to examine whether acutely or chronically exposure to low-frequency pulsed magnetic field (PMF) is adversely effect on contraction proteins and parameters of the uterine muscle in pregnancy terms of rats. Pregnant fifty-six rats divided into 8 groups (in each group, n= 7) according to pregnancy terms of rats; Exposed-pulsed magnetic field (Control, Early-PMF, Middle-PMF and Late-PMF of pregnancy terms) and unexposed groups. End of the pregnancy terms of rats, firstly were collected blood from rats for measure to contraction proteins levels (myosin light chain kinase (MYLK) and calmodulin (CAM)), then, uterine rings mounted in an organ baths. Uterine rings were allowed to equilibrate at 1.5 g tension for 60 min. The amplitude of contraction-force and contration-frequency in uterine rings was measured with isometric force transducers and MP35 systems. The uterine contraction parameters were analyzed as gram force (gf) and area (AUC;gxs). At the early-term of pregnancy, contraction force and AUC (under the curve) increased and at early and late terms of pregnancy, contraction force and frequency decreased in exposed to pulsed magnetic field groups compared to the control groups. Also, Myosin light chain kinase (MYLK) and calmodulin (CAM) levels significantly decreased in early and late terms of pregnancy rats in exposed to pulsed magnetic field groups compare to control groups. Findings suggest that acute or chronically non-invasive pulsed magnetic field exposure have no adversely affect in terms of pregnancy if the mother does not have any other symptomatic problem. Also non-invasive pulsed magnetic field application may help prevent unpleasant symptomatic progression in early and late terms of gestation. Therefore, there is a need for more detailed investigations whether acute or chronic exposure to pulsed magnetic field is affect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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