| Autor: |
Uysal, Ayşegül, Uslu, Serap, İnce, Ümit, Basdemir, Gulcin, İrban, Arzu, Oltulu, Fatih, Öktem, Gülperi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Popis: |
Aim: The aim of this study is to investigate the effects of intrauterine growth retardation depending onmaternal uterine artery ligation model, Wnt/?-catenin and S100 expression immunohistochemistry andhistomorphometrically on growth plate and bone tissue of fetal rats.Materials and Methods: Maternal rats were randomly divided into 3 groups (n=5). No surgery oranesthesia were applied in control group. Bilaterally the maternal uterine arteries were ligated ongestational day 18 in experimental group. Although all surgical procedures were performed in shamgroup, the uterine artery ligation were not made. Fetuses were taken on gestational day 20,thicknesses of growth plate and zones, trabecular number and thickness and cortical thickness wereevaluated with the histomorphometrically in samples from left proximal tibia. The expressions of ?catenin and S100 immunohistochemically were evaluated in the growth plate.Results: Thicknesses of growth plate (p0.05). Also trabecular numbers were lower (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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