Predictive value of bone scintigraphy in the diagnosis of prostate cancer bone metastases and comparison of verification methods
| Autor: | Kizilay F., Sahin M., Simsir A., Turna B., Cureklibatir I., Omur O. |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
positron emission tomography
retrospective study prostate specific antigen Diagnostic accuracy Article computer assisted tomography Magnetic resonance imaging transrectal ultrasonography male cross-sectional study controlled study furosemide human Gleason score nuclear magnetic resonance imaging bone scintiscanning bone metastasis Prostate cancer predictive value Bone metastases major clinical study human tissue Scintigraphy fluorodeoxyglucose f 18 sensitivity and specificity histopathology positron emission tomography-computed tomography femur measurement accuracy radiography |
| Popis: | Objective: There is no definitive consensus on the methods to verify suspicious lesions in bone scintigraphy (BS) for bone metastases in patients diagnosed with prostate cancer (PCa). In this study, we aimed to compare the accuracy rates of imaging modalities used for patients with suspected lesions in BS. Design: Retrospective cross-sectional study Setting: Tertiary university hospital Subjects: One hundred and twenty-six PCa patients with bone metastases Intervention: BS was applied to all patients for bone metastases screening. Patients underwent computerized tomography, X-ray, magnetic resonance imaging (MRI) and positron emission tomography for bone metastasis verification for suspicious lesions in BS. Main outcome measures: Comparison of metastasis detection rates of the imaging modalities and the evaluation of sensitivity of BS according to the location and the number of lesions. Results: MRI provided the highest rate of metastasis confirmation (81.3%). We found that the rate of detection of metastases in thoracal vertebrae, pubic bones, femur, L3-5 vertebrae and multiply involved cases was statistically significant (P |
| Databáze: | OpenAIRE |
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