Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia: A case report [Síndrome de Stevens-Johnson asociado al tratamiento con metotrexato de la leucemia linfoblástica aguda: A propósito de un caso]
| Autor: | Akinci B., Sivis Z.Ö., Sahin A., Karapinar D.Y., Balkan C., Kavakli K., Aydinok Y. |
|---|---|
| Přispěvatelé: | Ege Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Popis: | PubMed ID: 29756724 Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare mucocutaneous diseases which are associated with a prolonged course and potentially lethal outcome. They are mostly drug induced and mortality rates are very high. Althoughmostlyskinisinvolved,multipleorgansystemssuch as cardiovascular, pulmonary, gastrointestinal, and urinary systems may be affected. Here, we report a case of Stevens-Johnson Syndrome associated with methotrexate treatment who developed acute cardiac failure and gastrointestinal hemorrhage beside skin findings. He had been treated with intravenous immunglobulin and methylprednisolone succesfully and continued chemotherapy with methotrexate treatment again. © 2018 Sociedad Argentina de Pediatria. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|