Surface decontamination protocols for surgical treatment of peri-implantitis: A systematic review with meta-analysis

Autor: Baima, Giacomo, Citterio, Filippo, Romandini, Mario, Romano, Federica, Mariani, Giulia Maria, Buduneli, Nurcan, Aimetti, Mario
Jazyk: angličtina
Rok vydání: 2022
Předmět:
ISSN: 4202-0182
Popis: Objective To answer the following PICO question: In patients requiring surgical treatment of peri-implantitis (P), is any implant surface decontamination protocol (I) superior to others (C) in terms of clinical and radiographic parameters (O)? Methods Randomized clinical trials (RCTs) comparing two or more decontamination protocols as part of the surgical treatment of peri-implantitis were included. Two authors independently searched for eligible studies, screened titles and abstracts, did full-text analysis, extracted data, and performed the risk-of-bias assessment. Whenever possible, results were summarized through random effects meta-analyses. Results Twenty-two manuscripts reporting on 16 RCTs were included, testing mechanical, chemical and physical decontamination protocols. All of them resulted in an improvement in clinical parameters; however, the superiority of specific protocols over others is mainly based on single RCTs. The use of titanium brushes and implantoplasty showed favorable results as single decontamination methods. Meta-analyses indicated a lack of added effect of Er:Yag laser on probing pocket depth (PPD) reduction (n = 2, WMD = -0.24 mm, 95% confidence interval [CI] [-1.10; 0.63], p = .59); while systemic antimicrobials (amoxicillin or azithromycin) showed an added effect on treatment success ([PPD
Universita degli Studi di Torino within the CRUI-CARE Agreement
The authors kindly thank S. Isler, J. Lasserre, E. Romeo, S. Toma, and Y. de Waal, for providing more information and estimates about their studies, regardless of the final decision to include or not include them in the present systematic review. The authors received no financial support and declare no potential conflicts of interest with respect to the authorship and/or publication of this article. Open Access Funding provided by Universita degli Studi di Torino within the CRUI--CARE Agreement. Open Access Funding provided by Universita degli Studi di Torino within the CRUI-CARE Agreement.
Databáze: OpenAIRE