Myrtus communis L. Extract ve Apocynin'in Yüksek Yağ Diyetli Sıçanlarda Lens Oksidatif Hasarı ve Bor Düzeyleri Üzerine Etkileri
| Autor: | Yaşar R.K., Kuru D., Şen A., Şener G., Ercan F., Yarat A. |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
obesity
antioxidant animal experiment myrtle cholesterol blood level adverse event antioxidant activity Apocynin lipid blood level Wistar rat Diet High-Fat Article Antioxidants animal tissue Myrtus communis body weight Lens male high density lipoprotein cholesterol Animals Humans oxidative stress controlled study rat animal human Rats Wistar glutathione Boron plant leaf nonhuman Plant Extracts animal model catalase malonaldehyde acetophenone derivative Acetophenones superoxide dismutase Myrtus Rats Myrtus communis extract cataract plant extract blood sampling triacylglycerol lipid diet |
| Popis: | Objectives: Nutritional obesity causes oxidant damage in the body and cataract formation in the lenses by increasing the formation of free radicals. Myrtus communis leaf extracts (Myr) have antioxidant properties, and apocynin (Apo) is an effective NADPH-oxidase inhibitor. The data on tissue boron levels are quite lacking. The aim of this novel study was to investigate the effects of Myr and Apo treatment on boron levels and oxidative lens damage in rats fed a high-fat diet (HFD). Materials and Methods: Wistar albino male rats were randomly divided into four groups: the control group, HFD group, HFD + Myr group, and HFD + Apo group. Body weight and blood lipids were determined before and after the experiment. After decapitating the rats, the lenses were removed and homogenized. Catalase (CAT) and superoxide dismutase (SOD) activities and boron, malondialdehyde (MDA), and reduced glutathione (GSH) levels in the lens homogenates were determined. Results: The HFD increased serum triglyceride (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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