Helicobacter pylori eradication increases telomere length in gastric mucosa

Autor: Aslan, Rahmi, Bektaş, Ahmet, Bedir, Abdülkerim, Alaçam, Hasan, Aslan, Melek Suzer, Nar, Rukiye., Yıldırım, Beytullah, Gören, İbrahim
Přispěvatelé: Tıp Fakültesi
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Popis: PubMed ID: 23108080
Background/Aims: Our purpose in this study was to analyze telomere length and telomerase activity before and after eradication treatment in gastric mucosa in patients positive for H. pylori. Methodology: There were two groups: a control group (n=17) and a study group (n=21). For H. pylori eradication, the patients were administrated proton pump inhibitor (PPI) + clarithromycin + amoxicillin or PPI + metronidazole + tetracycline + bismuth for 14 days. Telomere length was analyzed with RT-PCR and telomerase activity with PCR-ELISA on biopsy specimens from the antrum. The result p
Databáze: OpenAIRE