Helicobacter pylori eradication increases telomere length in gastric mucosa
Autor: | Aslan, Rahmi, Bektaş, Ahmet, Bedir, Abdülkerim, Alaçam, Hasan, Aslan, Melek Suzer, Nar, Rukiye., Yıldırım, Beytullah, Gören, İbrahim |
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Přispěvatelé: | Tıp Fakültesi |
Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: | |
Popis: | PubMed ID: 23108080 Background/Aims: Our purpose in this study was to analyze telomere length and telomerase activity before and after eradication treatment in gastric mucosa in patients positive for H. pylori. Methodology: There were two groups: a control group (n=17) and a study group (n=21). For H. pylori eradication, the patients were administrated proton pump inhibitor (PPI) + clarithromycin + amoxicillin or PPI + metronidazole + tetracycline + bismuth for 14 days. Telomere length was analyzed with RT-PCR and telomerase activity with PCR-ELISA on biopsy specimens from the antrum. The result p |
Databáze: | OpenAIRE |
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