Clear cell ovarian carcinoma in a pregnant woman with a history of infertility, endometriosis and unsuccessful IVF treatment
| Autor: | Makrydimas, G., Sotiriadis, A., Paraskevaidis, E., Pavlidis, Nicholas, Agnantis, Niki J., Lolis, D. |
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| Přispěvatelé: | Pavlidis, Nicholas [0000-0002-2195-9961] |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Adult
Histology Clear cell cancer Ca 125 antigen Fertility promoting agent Symptom Endometriosis Pregnancy trimester Ca 125 Adenocarcinoma Cancer staging Cystectomy Hysterectomy Article Ovarian neoplasms Image analysis Disease association Ovarian cancer Pregnancy Case report Humans Female infertility First Clear cell Omentoplasty Amenorrhea and oligomenorrhea Clear cell carcinoma Transvaginal echography Neoplastic Laparotomy Fertilization in vitro Ovary carcinoma Gestational age Follow up Nuclear magnetic resonance imaging Pregnancy complications Clinical feature Treatment failure Infertility Diagnostic imaging Female Salpingooophorectomy Cesarean section Human |
| Zdroj: | European journal of gynaecological oncology |
| Popis: | Ovarian cancer in pregnancy is a very rare event. We present here the case of a 37-year-old woman in whom a clear cell ovarian carcinoma was diagnosed in the first trimester of pregnancy. This patient had a history of infertility, endometriosis and two previous unsuccessful attempts of in vitro fertilization. Transvaginal sonography at six gestational weeks revealed a 6 x 4 cm ovarian cyst with an internal papillary excrescence. The cyst persisted throughout the first trimester, whereas the initial CA 125 value of 226 U/ml dropped to 61 U/ ml at 12 gestational weeks. Exploratory laparotomy and cystectomy was performed at 14 weeks and the disease was classified as Stage Ic, arising in endometriosis. The couple decided to continue with pregnancy and the woman was followed by serial sonographic, MRI and CA 125 examinations. A cesarean section, hysterectomy, bilateral salpingo-oophorectomy and omentectomy was performed at 34 weeks. Histology and cytology were negative for recurrence. Four months later the woman and baby are doing well. We review cases of ovarian clear cell carcinoma diagnosed during pregnancy and discuss the association of endometriosis, infertility, infertility drugs and ovarian cancer. 24 5 438 441 |
| Databáze: | OpenAIRE |
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