| Autor: |
Yiallourou, Anneza I., Ekonomou, Emmanouel, Tsamadias, V., Nastos, Constantinos, Karapanos, Konstantinos, Papaconstantinou, Ioannis, Theodosopoulos, Theodosios, Contis, John, Papalarabros, E., Voros, Dionysios, Psychogios, J. |
| Přispěvatelé: |
Yiallourou, Anneza I. [0000-0003-1237-1661], Papaconstantinou, Ioannis [0000-0002-4614-9041], Nastos, Constantinos [0000-0001-5960-6494] |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Journal of B.U.ON. |
| Popis: |
Purpose: Both vitamin D and estrogens play an important role in breast cell growth and differentiation. Therefore, we hypothesized that Fokl polymorphism in the Vitamin D Receptor (VDR) gene, as well as PvuII polymorphism in the Estrogen Receptor (ESR) gene might be associated with progression of breast cancer. The aim of this study was to prospectively examine the association of these polymorphisms with histopathological features and prognosis among women with histologically proven breast cancer. Methods: Patient characteristics, tumor histopathology, and genotyping of one VDR polymorphism variant (Fokl) and one ER polymorphism variant (PvuII) were recorded. Patients were also routinely followed up. Results: There was a significant difference regarding nodal stage (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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