| Popis: |
As magnesium is an important trace element in bone and teeth, and plays a key role in bone metabolism, the aim of this study was to obtain magnesium substituted hydroxyapatite (MgHAP) and to assess its application potential. Upon synthesis, the changes in local structure and composition after irradiation and immersion in physiological solution and simulated fluid were followed by electron paramagnetic resonance (EPR) spectroscopy. Samples were also characterized by XRD, FTIR, SEM, EDS, AAS and TGA. The results showed that irradiation did not affect the composition and structure of Mg-HAP. After immersion in model media, the small amount of by-product of synthesis disappeared already after 24 h and Mg-HAP remained as the only phase. Also, the radical signals in EPR spectra faded or completely disappeared after 28 days in model media, which could indicate that the structure and composition of Mg-HAP both went through a kind of stabilization in conditions mimicking physiological ones. All these indicate that investigated Mg-HAP has good potential for biomedical application considering its behaviour in model media which imitate physiological conditions. X Serbian Ceramic Society Conference - Advanced Ceramics and Application : new frontiers in multifunctional material science and processing : program and the book of abstracts; September 26-27, 2022; Belgrade |
