The use of Inari FlowTriever® aspiration thrombectomy device for the management of acute pulmonary embolism : Initial experiences at the University Hospital of Split
| Autor: | Hafsmo, Therese Gangestad |
|---|---|
| Přispěvatelé: | Borovac, Josip Anđelo |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina
Inari FlowTriever aspiration pulmonary embolism liječenje plućne embolije Inari FlowTriever aspiracija perkutana trombektomija treatment of pulmonary embolism BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine percutaneous thrombectomy plućna embolija |
| Popis: | Objectives: Acute pulmonary embolism is a common medical emergency associated with a high risk of early mortality. The present thesis aimed to examine and describe the cohort of patients with acute pulmonary embolism (PE) who underwent catheter-directed percutaneous mechanical thromboaspiration with INARI FlowTriever® device and to assess safety and feasibility of this interventional method in this group of patients. Patients and methods: We retrospectively analyzed hospital records of all patients that underwent percutaneous mechanical thromboaspiration with INARI FlowTriever® device for acute PE since the adoption of this treatment method at the Cardiovascular Diseases Department, University Hospital of Split in April 2022 until June of 2023. Standard descriptive statistics were used to describe the cohort of PE patients and disease characteristics while for the assessment of the effectiveness of this treatment, we used a "before-after" pairwise student t-test for comparison concerning relevant procedural hemodynamic variables such as mean pulmonary artery pressure (mPAP) measured invasively, heart rate (HR) and peripheral oxygen saturation (SpO2). Results: A total of 14 patients who met clinical indications for mechanical thromboaspiration were analyzed while 13 procedures were performed. The mean age of the population was 61,7±14,2 years while 7 patients were women and 7 were men. Most of the PEs were saddle PEs affecting main branch bifurcation (50%), followed by bilateral (42,9%) and unilateral PE (7,1%). The vast majority of patients belonged to the intermediate-to-high risk category as per ESC guidelines (92,9%) while one patient was high-risk. The most common identifiable etiology of PE was recent major surgery (35,7%) while non-identifiable, idiopathic etiology was equally represented (35,7% of all cases). The mean length of hospital stay after procedure was 6 days (IQR 4,5-11,5). The median NT-proBNP levels and high-sensitivity cardiac troponin T values were 2033 pg/mL (IQR 387-4670) and 56,9 ng/L (IQR 46,9-84,8), respectively. Procedure-wise, mechanical thromboaspiration with INARI FlowTriever® device was associated with a significant reduction of mPAP (from 33,6±7,3 mmHg before the procedure to 16,6±5,6 mmHg after the procedure, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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