| Autor: |
Rotomskis, Augustinas, Grabauskaitė, Aida, Margevičiūtė, Ramunė, Germanavičius, Arūnas, Kaubrys, Gintaras Ferdinandas, Laukevičienė, Gabrielė, Žimkus, Andrius, Piraškevičiūtė, Neringa, Račkauskaitė, Justina |
| Jazyk: |
litevština |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Neurologijos seminarai, Vilnius, Rotas, 2015, T. 19, nr 63, p. 59-63 |
| ISSN: |
1392-3064 |
| Popis: |
Background. Currently, it is recognised that movement disorders, such as Parkinson’s and related diseases, also have a cognitive component and those diseases even progress in some patients to dementia. Therefore, a cognitive assessment is useful in evaluating movement disorders. There is a need for having more clinical tools for differential diagnostics between DLB and AD. The Addenbrooke’s Cognitive Examination-Revised can meet this need as it is a brief sensitive dementia screening test. The Lithuanian version of ACE-R (ACE-RLT) was shown to be able to detect dementia, but further research was still lacking in establishing the use of the ACE-R for differential diagnostics of AD and DLB. Accordingly, the aim of this study was to investigate the ability of the ACE-R to accurately differentiate mild-moderate Alzheimer’s disease from mild-moderate dementia with Lewy bodies. Participants and methods. Seventy three patients with early mild-moderate AD and 30 patients with mild-moderate DLB were evaluated with the ACE-R, the test which consists of the following domains: orientation, attention, memory, verbal fluency, language and visuospatial ability, with maximum total score 100. The results were compared with those obtained in 86 healthy controls. The one-way ANOVA, logistic-regression analysis, ROC analysis and Mann-Whitney U-test were done for statistical analysis. Results. In AD group neither age (p=0.060), nor gender (p=0.466) or education (p=0.206) had an effect on ACE-R scores. In DLB group neither age (p=0.249), nor gender (p=0.615) or education (p=0.360) had an effect on ACE-R scores. In control group both age (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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