| Autor: |
PERROTTA, Silverio, AMENDOLA G, LOCATELLI F, CONTE ML, ROSSI, Francesca, D'URZO G, NOBILI, Bruno |
| Přispěvatelé: |
Perrotta, Silverio, Amendola, G, Locatelli, F, Conte, Ml, Rossi, Francesca, D'Urzo, G, Nobili, Bruno |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
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| Popis: |
We report on 14 children (seven boys, seven girls) with chronic idiopathic thrombocytopenic purpura (ITP) refractory to multiple treatments, who were given a short-term therapy (range between 6 and 10 weeks) with high doses of cyclosporin A (CyA) (median, 10 mg/kg/d). Six patients experienced adverse events and one developed severe systemic mycosis during therapy. A complete response (CR) was observed in four patients and a partial response (PR) in three patients. Only the four CR patients, who were all girls, had a sustained response. These data suggest that CyA may be effective in some children with chronic symptomatic ITP. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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