PREVENTION OF CELL DEATH DUE TO THERMAL OSTEONECROSIS BY USING NEWLY DESIGNED MEDICAL DRILLS
| Autor: | Babić, Slaven |
|---|---|
| Přispěvatelé: | Matejčić, Aljoša |
| Jazyk: | chorvatština |
| Rok vydání: | 2022 |
| Předmět: |
traumatologija
PRIRODNE ZNANOSTI. Biologija udc:57(043.3) termička osteonekroza surgical drills smrt stanice medicinska svrdla Biološke znanosti. Fizička antropologija. Bioraznolikost cell death thermal osteonecrosis NATURAL SCIENCES. Biology orthopaedic surgery Biological sciences. Physical anthropology. Biodiversity ortopedija |
| Popis: | Termička osteonekroza je oštećenje kosti koje nastaje tijekom medicinskih intervencija u ortopediji i traumatologiji. Pri bušenju kosti dolazi do porasta temperature uz mjesto bušenja. Kad porast temperature i vrijeme izlaganja povišenoj temperaturi premašuju kritične razine, nastaju nepovratna oštećenja stanica. Da bi se termičko oštećenje kosti preveniralo, mjesto bušenja potrebno je hladiti ili rabiti drukčiji dizajn svrdala od dosadašnjih, koja manje zagrijavaju okolno tkivo. U tu svrhu dizajnirana su dvostupnjevana svrdla s više kombinacija užeg i šireg stupnja te je uspoređena razlika porasta temperature sa standardnim svrdlima bušenjem na umjetnom materijalu. Bušenje na kostima izvedeno je odabranim kombinacijama svrdala s najvećim potencijalom smanjenja porasta temperature, a uzorci koštanog tkiva s ruba provrta kvantitativno su histološki analizirani. Ovo istraživanje pokazalo je da se kod dvostupnjevanih svrdala razvijaju manje temperaturu okolne kosti od standardnih svrdala te da je oštećenje stanica proporcionalno porastu temperature. Dvostupnjevana svrdla primjenjiva su u ortopediji i traumatologiji Thermal osteonecrosis is bone damage that occurs during medical interventions in orthopaedics and traumatology. The temperature in the procedures of drilling bones rises near the drilling site. When the temperature rises and the time of exposure to elevated temperature exceeds critical levels, irreversible cell damage occurs. In order to prevent thermal damage to the bone, it is necessary to cool the drilling site or use a different design of drills, which causes less temperatures and less damage to the surrounding tissue. For this purpose, two-stage drills with several combinations of narrower and wider stages were designed, and the difference in temperature rise was compared with standard drill bits, by drilling on artificial material. Drilling on bone tissue samples was performed with selected drill combinations which proved to have the greatest potential to reduce the temperature rise. These samples were quantitatively histologically analyzed. This study showed that two-stage drills develop a lower bone temperature than standard drills and that cell damage is proportional to temperature rise. Twostage drills are applicable in orthopaedic surgery. |
| Databáze: | OpenAIRE |
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