Autor: |
Hurduc, V., Plesca, D., Dragomir, D., Sajin, M., Vandenplas, Yvan |
Přispěvatelé: |
Pediatrics |
Jazyk: |
angličtina |
Rok vydání: |
2009 |
Předmět: |
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Popis: |
AIM: The failure rate of Helicobacter pylori (H. pylori) eradication imposes the assessment of new options. SUBJECTS AND METHODS: A prospective open study was performed in 90 symptomatic children (range 3-18 years) with H. pylori infection, randomized in two groups: control (42 patients) and intervention group (48 patients). Both groups were treated with the standard triple eradication therapy (omeprazole/esomeprazole, amoxicillin and clarithromycin) for 7-10 days. The intervention group was also treated with Saccharomyces boulardii (S. boulardii), 250 mg b.i.d., for 4 weeks. The eradication rate of H. pylori was assessed by the same methods (urease test and histology) 4-6 weeks after treatment. Adverse events and compliance were evaluated after 7 and 28 days of treatment. The Chi-square test was used for statistical evaluation (p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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