| Autor: |
Van Den Berge, D., Bruyneel, E., Distelmans, W., Van Belle, S., Krikonian, A., Breillout, F., Storme, G. |
| Přispěvatelé: |
Radiation Therapy, Clinical sciences, Mental Health and Wellbeing research group, Supportive and palliative care, Translational Radiation Oncology and Physics, Vrije Universiteit Brussel, Centre for Oncology, Medical Imaging and Physical Sciences |
| Jazyk: |
angličtina |
| Rok vydání: |
1993 |
| Předmět: |
|
| Popis: |
5'-nor-anhydrovinblastine (Navelbine®) is a hemisynthetic Vinca alkaloid for which a selectivity for mitotic microtubules has been demonstrated. In previous studies, we have demonstrated an anti-invasive effect of other Vinca alkaloids. Here the results of in vitro and in vivo assays concerning the effect of 5'-nor-anhydrovinblastine on growth and invasion of MO4 cells are presented. It is demonstrated that at cytostatic concentrations, 5'-nor-anhydrovinblastine also has an anti-invasive effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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