Cerebrospinal Fluid Amyloid beta(40) Is Decreased in Cerebral Amyloid Angiopathy

Autor: Verbeek, Marcel, Kremer, Hubertus Petrus Henricus, Olde Rikkert, M, Van Domburg, Peter, Skehan, Maureen, Greenberg, Steven
Přispěvatelé: Internal Medicine Specializations
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Popis: Cerebral amyloid angiopathy is caused by deposition of the amyloid P protein in the cerebral vasculature. In analogy to previous observations in Alzheimer disease, we hypothesized that analysis of amyloid beta(40) and beta(42) proteins in the cerebrospinal fluid might serve as a molecular biomarker. We observed strongly decreased cerebrospinal fluid amyloid beta(40) (P
Databáze: OpenAIRE