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Recently, personalised approaches in the treatment of several chronic diseases such as cancer, osteoporosis, autoimmune and joint diseases are being translated from the research to the clinical practice. The goal of the personalised medicine is individualisation of therapy to achieve its optimal efficiency and safety. Laboratory medicine professionals play a key role in this process, since they provide the information needed to optimize the therapy. Researchers at the Chair of Clinical Biochemistry and Laboratory Medicine have been developing several fields of personalised (or precision) medicine, such as pharmacogenomics, nutrigenomics and cell ther-persoapy, in the context of various diseases, such as acute lymphoblastic leukaemia, chronic lymphocytic leukaemia, osteoporosis, degenerative joint disease and autoimmune diseases. Further translation of these approaches into clinical practice depends on the level of education of health professionals in this field. Thus, the incorporation of these topics into study programs is of the utmost importance. Personalizirani pristopi v obravnavi številnih kroničnih bolezni, kot so rak, osteoporoza, avtoimunske in sklepne bolezni, v zadnjem desetletju nezadržno prodirajo iz raziskovalne sfere v klinično prakso. Cilj teh pristopov je, da na osnovi genetskih in drugih dejavnikov individualiziramo zdravljenje v smislu doseganja optimalnih učinkovitosti in varnosti. Ključno vlogo v tem procesu imajo poleg zdravnikov in farmacevtov tudi strokovnjaki laboratorijske medicine, saj zagotavljajo informacije, na osnovi katerih oblikujemo optimalno zdravljenje za določenega bolnika. Na Katedri za klinično biokemijo in laboratorijsko medicino razvijamo različna področja personalizirane (oz. precizne) medicine, kot so farmakogenomika, nutrigenomika, in celično zdravljenje, in sicer v kontekstu različnih bolezni, kot so akutna limfoblastna levkemija, kronična limfatična levkemija, osteoporoza in degenerativne bolezni sklepov ter avtoimunske bolezni. Nadaljnja translacija omenjenih pristopov v klinično prakso je odvisna od stopnje izobraženosti zdravstvenih delavcev na tem področju. Zato je pomemben cilj Katedre in Fakultete za farmacijo uvajanje teh vsebin tudi v študijske programe. |
