Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history:pooled analysis of ACLIFORM and AUGMENT

Autor: D'Urzo, Anthony D., Singh, Dave, Donohue, James F., Kerwin, Edward M., Ribera, Anna, Molins, Eduard, Chuecos, Ferran, Jarreta, Diana, Gil, Esther Garcia
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: D'Urzo, A D, Singh, D, Donohue, J F, Kerwin, E M, Ribera, A, Molins, E, Chuecos, F, Jarreta, D & Gil, E G 2019, ' Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history : pooled analysis of ACLIFORM and AUGMENT ', International journal of chronic obstructive pulmonary disease, vol. 14, pp. 479-491 . https://doi.org/10.2147/COPD.S185502
DOI: 10.2147/COPD.S185502
Popis: Background: Aclidinium/formoterol 400/12 µg is a twice-daily maintenance bronchodilator for COPD. This post hoc study evaluated aclidinium/formoterol vs aclidinium 400 µg, formoterol 12 µg, or placebo in patient subgroups. Patients and methods: Data were pooled from two 24-week Phase III clinical trials (ACLIFORM and AUGMENT). Patients (N=3,394) were analyzed by baseline airflow obstruction severity (moderate/severe), age (
Databáze: OpenAIRE