Biological bioreactor characterization by means of an Escherichia coli model process

Autor: von Blarer, Damian, Senn, Yannick, Kienle, Klaus, Schirmer, Cedric, Blaschczok, Katharina, Husemann, Ute, Greller, Gerhard, Leupold, Marco, Rupprecht, Jens, Glöckler, Rainer, Eibl, Dieter
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Popis: Bioreactor characterization has mainly been based on bioengineering parameters such as oxygen transfer, mixing time or power input. With the wide variety of single-use and re-usable stainless steel bioreactors the characterization and qualification of bioreactors became important. In order to guarantee reliable comparison of the different bioreactor types, standardized biological methods are needed in addition. For this reason, DECHEMA`s expert group on single-use technology has developed guidelines providing a set of uniform procedures which allow cross-system comparison independent of the manufacturer’s data, applicable for both re-usable and single-use systems. In this study, bioengineering and biological characterization were carried out according to DECHEMA’s guidelines for two stainless steel stirred tank bioreactors with working volumes of 30 and 100L.
Databáze: OpenAIRE