Theonella swinhoei as a source of anti-inflammatory cyclopeptides
| Autor: | FESTA, CARMEN, DE MARINO, SIMONA, D'AURIA, MARIA VALERIA, BUCCI, MARIAROSARIA, VELLECCO, VALENTINA, ZAMPELLA, ANGELA, M. C. Monti, C. Debitus |
|---|---|
| Přispěvatelé: | Società chimica italiana, Festa, Carmen, DE MARINO, Simona, D'Auria, MARIA VALERIA, M. C., Monti, Bucci, Mariarosaria, Vellecco, Valentina, C., Debitu, Zampella, Angela |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Popis: | As a part of our systematic study on secondary metabolites from marine organisms collected at Solomon Islands, we found a single specimen of the sponge Theonella swinhoei as an extraordinary source of anti-inflammatory cyclic cyclopeptides, such as perthamides C-K and solomonamides. Perthamides C-K are endowed of promising anti-inflammatory activity. The isolation of this small library of peptides allowed us to delineate a structure-activity relationship. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|