Autor: |
LEVANTINO, Matteo, CUPANE, Antonio, Cammarata, M, Vallone, B, Brunori, M |
Přispěvatelé: |
Levantino, M, Cammarata, M, Vallone, B, Brunori, M, Cupane, A. |
Jazyk: |
angličtina |
Rok vydání: |
2013 |
Předmět: |
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Popis: |
Time-resolved wide-angle X-ray scattering (TR-WAXS) is a recently developed technique allowing to probe global structural changes of proteins in solution. We have used TR-WAXS to investigate large conformational changes of heme proteins (wild-type and mutant hemoglobin, neuroglobin, etc.) that cannot take place when these macromolecules are in a crystalline environment. Our data revealed detailed information on kinetic and thermodynamic properties of the investigated proteins and demonstrate the potentiality of the TR-WAXS technique. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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