| Autor: |
Porrello,C, Gullo,R, Gagliardo,MC, Vaglica,A, Palazzolo,M, Giangregorio,F, Iadicola,D, Catanzaro,A, Scerrino,G, Lo Faso,F, carini,F, Tomasello,G |
| Přispěvatelé: |
Porrello,C, Gullo,R, Gagliardo,MC, Vaglica,A, Palazzolo,M, Giangregorio,F, Iadicola,D, Catanzaro,A, Scerrino,G, Lo Faso,F, carini,F, Tomasello,G |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Aim: The present study aimed to demonstrate that computed tomography-guided transthoracic needle biopsy (TTNB) is a safe procedure that gives a more accurate pre-operative tissue diagnosis for peripheral lung nodules than transthoracic needle aspiration, obtaining suitable samples for molecular test in lung adenocarcinomas. Patients and methods: Between December 2016 and March 2018 at Thoracic Surgery Department of the University of Palermo - Policlinico Paolo Giaccone Hospital, TTNB was performed in 42 patients with computed tomography-detected peripheral lung nodules > 10 mm, using 16-18 -Gauge tru-Cut needles. Results: With TTNB, we have estimated an accuracy for tissue diagnosis of 97,6%. At the molecular test, EGFR overexpression and ALK mutation resulted positive for 12/23 patients with lung adenocarcinoma. Conclusion: TTNB has showed a low rate of complications and it is adoptable as standard diagnostic procedure for peripheral lung nodules. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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