| Autor: |
M Cattalini, S Della Paolera, F Zunica, C Bracaglia, M Giangreco, L Verdoni, A Meini, R Sottile, R Caorsi, G Zuccotti, M Fabi, D Montin, A. Meneghel, A Consolaro, R M Delle Piane, MC Maggio, F La Torre, A Marchesi, G Simonini, A Villani, R Cimaz, A Ravelli, A Taddio |
| Přispěvatelé: |
M Cattalini, S Della Paolera, F Zunica, C Bracaglia, M Giangreco, L Verdoni, A Meini, R Sottile, R Caorsi, G Zuccotti, M Fabi, D Montin, A. Meneghel, A Consolaro, R M Delle Piane, MC Maggio, F La Torre, A Marchesi, G Simonini, A Villani, R Cimaz, A Ravelli, A Taddio |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Introduction: Italy was affected by the SARS-CoV-2 epidemic after its outbreak in China. With a 4-weeks delay after the peak in adults, we observed an abnormal number of patients with characteristics of a multi-inflammatory disease and similarities with Kawasaki Disease (KD). Others reported similar cases, defined PIMS-TS or MIS-C.1,2 Objectives: To better characterize clinical features and treatment response of PIMS-TS and to explore its relationship with KD. Methods: We conducted an observational, retrospective, multicenter study. On April 24th-2020 the Rheumatology Study Group of the Italian Pediatric Society launched a national online survey, to enroll patients diagnosed with KD or with a multisystem inflammatory disease between February 1st 2020 and May 31st. The population was then divided into two different groups: 1) Classical and incomplete KD, named Kawasaki Disease Group (KDG); 2) KD-like multi-inflammatory syndrome, named KawaCOVID (KCG). An expert panel of pediatric rheumatologists re-analyzed every single patient to ensure appropriate classification. Data were collected with an online database. Results: 149 cases were studied, 96 with KDG and 53 with KCG. The two population significantly differed for clinical characteristics (see table 1). Lymphopenia, higher CRP levels, elevated Ferritin and Troponin-T characterized KCG such as lower WBC and platelets (all p values |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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