| Popis: |
Asthma frequently coexists with allergic rhinitis (AR) symptoms. There are limited data about asthmatic symptoms in children with nonallergic rhinitis (Non-AR). Estimate frequency of asthmatic symptoms and prevalence of bronchial hyperresponsiveness (BHR) in children with ANN and Non-ANN. The study included children age 8-14 years, surveyed because of chronic non-infectious rhinitis symptoms (< 4 weeks, more than 4 days/week), without established asthma diagnosis and without asthma or allergic treatment. Polish version of ISAAC questionnaire, exercise challenge test with tread mill were used. Relative decrease of FEV_{1} (delta FEV^{1}) at least 10% indicated BHR. Atopy was established by prick tests with 10 aeroallergens. The questionnaire survey: in children with AR (n = 63) and Non-AR (n = 49) wheeze ever has been observed in 36% and 55% (p = = 0.076), respectively; and in the last year: wheeze in 21% and 41% (p = 0.034); asthma attacks (> 3 x/year) in 5% and 4% (p = 0.138); night awaking in 9% and 17% (p = 0.342); post exercise wheeze in 16% and 14% (p = 0.973); night cough in 64% and 71% (p = 0.494). The exercise challenge test: in children with AR and Non-AR, BHR were observed in 28% and 12% (p = 0.077), respectively. In these two groups of children, medians (95% CI for median) for delta FEV1 were, respectively: 5.9 (4.8-8.0) and 4.1 (2.5-5.7) (p = 0.072). Wheeze in the last year significantly more often occurred in children with Non-AR than with AR. However, frequency of BHR and results of exercise challenge tests were comparable in both groups of children. ANN and Non-AR in children could be considered as the risk factor of asthma. |
