| Popis: |
In the present study, we investigated cyclodextrine as an excipient for tablet. In the pharmaceutical industry, the particulate ingredients are often granulated to improve their flowability and uniformity. A fluidized bed gas-solid drying is usually followed to remove the moisture that is introduced during the granulation. Fluidized bed granulation is a widely applied wet granulation technique in the pharmaceutical industry, exhibiting some technological advantages compared to the multistage wet granulation methods. Of the three available cyclodextrin forms, b-cyclodextrin is the most commonly used cyclodextrin in pharmaceutical formulations and the best studied cyclodextrin in humans. The possibility of using b-cyclodextrin in the production process of solid dosage forms using the technology of drying in a fluidized bed was confirmed. |
