Evaluation of corneal layers and anterior sclera in patients with primary Sjögren's syndrome
| Autor: | Pekel G, Taşçı M, Bahar A, Pekel E, Çetin EN, Martin Ç, Çobankara V |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
genetic structures
Adult Aged Case-Control Studies Cornea/diagnostic imaging/*pathology Cross-Sectional Studies Female Humans Male Middle Aged Reference Values Sclera/diagnostic imaging/*pathology Sjogren's Syndrome/*pathology/physiopathology Tears/physiology Tomography Optical Coherence/methods sense organs eye diseases |
| Popis: | PURPOSE: We aimed to compare the thickness of anterior sclera, corneal layers, and pre-ocular tear film between patients with primary Sjögren's syndrome and healthy individuals. METHODS: Fifty-one patients with primary Sjögren's syndrome and 41 healthy control participants were recruited in this cross-sectional and comparative study. The thickness of the pre-ocular tear film, corneal epithelium, Bowman's layer, stroma, Descemet's membrane, and endothelium were measured on the corneal apex. Anterior scleral thickness was measured at distances of 1 mm and 3 mm from the limbus. The anterior segment module of spectral-domain optical coherence tomography was used to measure thicknesses of pre-ocular tear film, corneal layers, and anterior sclera. RESULTS: Tear film thickness, Schirmer's test, and tear break up time values were significantly lower in the Sjögren's disease group than in the healthy controls (p |
| Databáze: | OpenAIRE |
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