Corneal melanosis successfully treated using topical mitomycin-C and alcohol corneal epitheliectomy: a 3-year follow-up case report
| Autor: | Balcı M, Yağcı R, Güler E, Haltaş H, Duman R, Hepşen İF |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
genetic structures
sense organs eye diseases Aged Antibiotics Antineoplastic/*therapeutic use Combined Modality Therapy Conjunctival Neoplasms/complications Corneal Diseases/*drug therapy/etiology Female Follow-Up Studies Humans Melanoma/complications Melanosis/*drug therapy/etiology Mitomycin/*therapeutic use Treatment Outcome Visual Acuity |
| Popis: | We report a case of primary acquired corneal melanosis without atypia associated with corneal haze in a patient with a history of limbal malignant melanoma and the effect of mitomycin-C. A 75-year-old woman with a history of limbal malignant melanoma presented with loss of vision in right eye. Corneal examination showed a patchy melanotic pigmentation with a central haze. Topical mitomycin-C improved visual acuity and corneal haze. However, the pigmented lesions persisted, and they were removed with alcohol corneal epitheliectomy. Histopathological examination demonstrated primary acquired melanosis without atypia. The lesions were successfully removed, and there were no recurrences during the follow-up period of 36 months. The association of conjunctival and corneal melanosis without atypia is a rare condition. In addition, co-existence of central corneal haze and melanosis may decrease visual acuity. Topical mitomycin-C and alcohol corneal epitheliectomy can be useful treatments in this condition. |
| Databáze: | OpenAIRE |
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