Primary CNS lymphoma with intravitreal metastasis : using vitreous cavity samples to monitor response to therapy

Autor:	Fenech, Matthew T., Aquilina, Nicola, Grech Hardie, John, Pirotta, Suzanne T., Fenech, Thomas, Debono, Patricia
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	sense organs eye diseases Lymphomas -- Case studies Vitrectomy -- Case studies
Popis:	A fifty-eight year old male patient presented to the ophthalmic department with a 3 day history of reduced visual acuity, blurred vision and floaters, associated with recent lethargy, headaches and behavioural changes. Fundal examination revealed a bilateral vitritis. Steroid therapy was started. MRI of the brain revealed multiple hypodense and hyperdense lesions. Vitrectomy was performed in view of the poor response to steroids. A biopsy showed non-hodgkin B-Cell lymphoma. The patient was started on intravenous Methotrexate and Cytarabine. Repeat vitreous cavity biopsies were performed in order to assess response to therapy. All biopsies to date have revealed evidence of on-going lymphoma. peer-reviewed
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=od______3549::a7b3d9639701a24182c6853b2560df12 Zobrazit plný text záznamu