Reproductive outcomes after laparoscopic surgery in infertile women affected by ovarian endometriomas, with or without in vitro fertilisation

Autor: Ban Frangež, Helena, Vrtačnik-Bokal, Eda, Štimpfel, Martin, Divjak Budihna, Teja, Gulino, Ferdinando Antonio, Garzon, Simone, Ghezzi, Fabio, Alkatout, Ibrahim, Gitas, Georgios, Laganà, Antonio Simone
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of obstetrics and gynaecology, vol. 42, no. 5, pp. 1293-1300, 2022.
ISSN: 0144-3615
Popis: We performed a retrospective cohort study, namely “Surgery and ART for Endometriomas” (SAFE) trial (Clinical Trial ID: NCT03717870), including women who underwent laparoscopic cystectomy for endometrioma before first IVF and compared their reproductive outcomes with the ones of women without endometriosis and with unexplained infertility, tubal factor or male factor infertility. We found that women who underwent previous laparoscopic cystectomy for endometrioma had higher FSH and LH levels between the 2nd and 5th day of the cycle before IVF, required higher doses of gonadotrophins for ovarian stimulation and had a lower number of retrieved oocytes compared with other types of infertility. Nevertheless, pregnancy and delivery rates remain comparable to other causes of infertility. In addition, differences in ovarian stimulation parameters between endometriosis and other types of infertility lost significance with the increase of women’s age. These pieces of information can be considered useful to make adequate counselling about reproductive outcomes for infertile women with ovarian endometriomas and allow a proper decision-making approach shared with the patient.
Databáze: OpenAIRE