| Autor: |
García, Manuela Emila, Woodruff, Shannon R., Hellemann, Erich, Tsarevsky, Nicolay V., Gil, Roberto Ricardo |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| DOI: |
10.1002/mrc.4400/full |
| Popis: |
Residual dipolar couplings (RDCs) constitute an important NMR parameter for structural elucidation in all areas of chemistry. In this study, di(ethylene glycol) methyl ether methacrylate (DEGMEMA)-basedgelsare introduced as alignment media for the measurement of RDCs of small organic molecules in polar solvents such as methanol. The low viscosity of methanol permits the execution of J-scaled BIRD HSQC experimentsthat yield very sharp lines in anisotropic conditions. The gels have excellent mechanical properties, and their compression and expansion in the swollen state can be reversed and performed multiple times. This process enables the easy loading and release of analytes. The excellent performance of these new aligning gels is demonstrated by analyzing the structure of the alkaloid retrorsine. Fil: García, Manuela Emila. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina. University Of Carnegie Mellon; Estados Unidos Fil: Woodruff, Shannon R.. University Of Carnegie Mellon; Estados Unidos. Southern Methodist University; Estados Unidos Fil: Hellemann, Erich. University Of Carnegie Mellon; Estados Unidos Fil: Tsarevsky, Nicolay V.. University Of Carnegie Mellon; Estados Unidos Fil: Gil, Roberto Ricardo. University Of Carnegie Mellon; Estados Unidos |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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