Synthesis of novel functionalized N,N-disubstituted aminothiazoles

Autor: Naruševičiūtė, K., Grybaitė, B., Sapijanskaitė-Banevič, B., Vaickelionienė, R., Anusevičius, K., Mickevičius, V.
Přispěvatelé: Vilniaus universitetas, Kauno technologijos universitetas, Valstybinis mokslinių tyrimų institutas Fizinių ir technologijos mokslų centras, Lietuvos chemikų draugija, Lietuvos mokslų akademija
Jazyk: angličtina
Rok vydání: 2023
Popis: A large number of chemotherapeutics are developed for medicinal use in nowadays but the increasing resistance of pathogens to available pharmaceuticals has created an essential demand for new efficient classes of antimicrobial agents. A unique small-ring heterocycle – thiazole containing nitrogen and sulphur atoms, play an important role in medicinal chemistry and is widely used in the development of bioactive compounds, drugs, as well as industrial products [1, 2]. Pharmaceuticals based on thiazole and its derivatives are used in medical practice for the treatment of hypertension, Alzheimer's disease, diabetes, schizophrenia, allergies they act as anticancer, antimicrobial, antifungal agents [3]. [...]
Databáze: OpenAIRE