| Autor: |
Gelminauskaitė, R., Grybaitė, B., Mickevičiūtė, E. |
| Přispěvatelé: |
Vilniaus universitetas, Kauno technologijos universitetas, Valstybinis mokslinių tyrimų institutas Fizinių ir technologijos mokslų centras, Lietuvos chemikų draugija, Lietuvos mokslų akademija |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Popis: |
β-Amino acids are promising intermediates in organic, bioorganic, medicinal, and peptide chemistry. Great number of natural and synthetic compounds, containing b-alanine moiety, are biologically active and find application in pharmacy. A large number of chemotherapeutics are developed for medicinal use nowadays but the increasing resistance of pathogens to available pharmaceuticals has created an essential demand for new efficient classes of antimicrobial agents. Given the promising pharmacological potential of highly functionalized carbocyclic β-amino acids bearing hydroxy, azido, amino, or fluoro groups can be as building blocks in the synthesis of novel bioactive compounds. The aim of this work was to synthesize compounds containing the above-mentioned two fragments and to determine the biological properties of the obtained compounds. [1-3] [...] |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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