Frontiers in Cardiovascular Medicine / Impact of pacing mode and different echocardiographic parameters on cardiac output (PADIAC)

Autor: Blessberger, Hermann, Kammler, Jürgen, Kellermair, Jörg, Kiblböck, Daniel, Nahler, Alexander, Hrncic, Denis, Saleh, Karim, Schwarz, Stefan, Christian, Reiter, Fellner, Alexaner, Eppacher, Christian, Sheldon, Todd J., Steinwender, Clemens
Jazyk: němčina
Rok vydání: 2023
Předmět:
Popis: Introduction: The extent of the hemodynamic benefit from AV-synchronous pacing in patients with sinus rhythm and AV block is not completely understood. Thus, we systematically investigated the association of an array of echocardiographic and epidemiological parameters with the change in cardiac output depending on the stimulation mode (AV-synchronous or AV-asynchronous pacing). Methods: Patients in sinus rhythm after previous dual chamber pacemaker implantation underwent a thorough basic echocardiographic assessment of diastolic and systolic left ventricular function, and atrial function (26 echo parameters, including novel speckle tracking strain measurements). Then, stroke volume was measured with AV-synchronous (DDD) and AV-asynchronous (VVI) pacing. Each patient represented their own control, and the sequence of stroke volume measurements was randomized. Results: In this prospective single-center study (NCT04068233, registration August 22nd 2019), we recruited 40 individuals. The stroke volume was higher in all patients when applying AV-synchronous DDD pacing [median increase 12.8 ml (16.9%), P
Databáze: OpenAIRE