Autor: |
Doğru, Arzum Güler, Toprak, Ömer, Üner, Devrim Deniz, İzol, Bozan Serhat, Kaplan, İbrahim, Doğru, Mehmet, İpek, Fikret |
Přispěvatelé: |
Dicle Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Bölümü, Doğru, Arzum Güler, Toprak, Ömer, Kaplan, İbrahim, Doğru, Mehmet, İpek, Fikret |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Popis: |
WOS:000619650600002 Abstract OBJECTIVE: To evaluate the outcome of initial periodontal therapy and additional diode laser decontamination therapy on clinical parameters and the amount of tumor necrosis factor alpha (TNF-alpha) in gingival crevicular fluid (GCF) in patients with chronic periodontitis. STUDY DESIGN: The study included 22 patients who were diagnosed with chronic periodontitis and who had at least 1 (>= 5 mm) periodontal pocket in the posterior region of each upper left hemi-arcade. The study was designed as a split-mouth study involving mechanical therapy on the right side and nonsurgical periodontal therapy plus diode laser decontamination therapy on the left side. RESULTS: A statistically significant decrease was observed in clinical parameters at 3 months when compared to the values at baseline in both treatment areas. The change in clinical parameters at 3 months after therapy was not significantly different between the groups (p>0.05). The comparison of GCF TNF-alpha levels at baseline and at 3 months in the 2 treatment areas identified significant changes in the TNF-alpha levels in the hemi-arcade treated with laser diode contamination therapy, whereas the changes in the hemi-arcade treated with nonsurgical periodontal therapy were not significant (p>0.05). A between-group comparison revealed no statistically significant difference at 3 months post-therapy, while the difference at 1 month was found to be statistically significant. CONCLUSION: The study found that laser therapy in addition to nonsurgical periodontal therapy has a positive effect on the clinical parameters and proinflammatory TNF-alpha levels in the early period but makes no contribution in the long term. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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