| Autor: |
Freire Rosales, Manuel José, Bernal Méndez, Joaquín, Pérez Izquierdo, Alberto Tomás |
| Přispěvatelé: |
Universidad de Sevilla. Departamento de Física Aplicada III, Universidad de Sevilla. Departamento de Electrónica y Electromagnetismo |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Popis: |
Transcranial static magnetic stimulation is a novel noninvasive method of reduction of the cortical excitability in certain neurological diseases that makes use of static magnetic fields generated by permanent magnets. By contrast, ordinary transcranial magnetic stimulation makes use of pulsed magnetic fields generated by strong currents. Whereas the physical principle underlying ordinary transcranial magnetic stimulation is well known, that is, the Faraday´s law, the physical mechanism that explains the interaction between neurons and static magnetic fields in transcranial static magnetic stimulation remains unclear. In the present work, it is discussed the possibility that this mechanism might be the Lorentz force exerted on the ions flowing along the membrane channels of neurons. The overall effect of the static magnetic field would be to introduce an additional friction between the ions and the walls of the membrane channels, thus reducing its conductance. Calculations performed by using a Hodgkin–Huxley model demonstrate that even a slight reduction of the conductance of the membrane channels can lead to the suppression of the action potential, thus inhibiting neuronal activity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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