Hair Sample Analysis as a Method of Monitoring Exposure to Bisphenol A in Dogs

Autor: Makowska, Krystyna, Martín Bueno, Julia, Rychlik, Andrzej, Aparicio Gómez, Irene, Santos Morcillo, Juan Luis, Alonso Álvarez, Esteban, Gonkowski, SŁawomir
Přispěvatelé: Universidad de Sevilla. Departamento de Química Analítica, Universidad de Sevilla. FQM344: Análisis Químico Industrial y Medioambiental
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Popis: Bisphenol A (BPA) is an organic substance widely used in the plastics industry. It penetrates food and environment and, as an endocrine disruptor, has detrimental effects on human organisms. Pet animals, which live in the immediate vicinity of humans, are also exposed to BPA; however, knowledge regarding the exposure of dogs to this substance is extremely scarce. This is the first study in which hair analysis has been used to biomonitor BPA in 30 dogs using liquid chromatography and tandem mass spectrometry techniques. The presence of BPA in concentration levels above the method detection limit (1.25 ng/g) was noted in 93.33% of samples. BPA concentration levels were found to range from 7.05 ng/g to 436 ng/g (mean 81.30 ng/g). Statistically significant differences in BPA concentration levels were found between animals with physiological weight and animals with abnormal weight (skinny and obese). In turn, differences between males and females, as well as between young, middle-aged and old dogs, were not statistically significant. The obtained results have clearly shown that hair analysis is a useful method to evaluate the exposure of dogs to BPA. This study also confirmed that dogs are exposed to BPA to a large extent, and this substance may play a role as a pathological factor in this animal species. However, many aspects connected to the influence of BPA on canine health status are unclear and need further study. Minister of Education and Science (Sapin) program entitled “Regional Initiative of Excellence” for the years 2019-2022, Project No. 010/RID/2018/19
Databáze: OpenAIRE