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In this study, which is a widely used organophosphate intoxication and biochemical changes caused by malatyonun Royal Jelly to determine the preventive and curative properties. For this study, the experimental rats were divided into 6 groups. Sham group (group 1) injection of any substance made to rats. Individuals (Group 2) The rats are used as carriers chemicals (methyl cellulose, DMSO, PBS) was applied. malathion group (group 3) subcutaneous administration to rats, 0.8 g/kg dose was injected malathion. Royal Jelly group (group 4) rats, 100 mg/kg was given by gavage Royal Jelly. Royal Jelly+OP group (group 5) rats, subcutaneously 0.8 g/kg 1 hour before the injection of malathion Royal Jelly 100 mg/kg administered by gavage. OP + Royal Jelly group (group 6) subcutaneously in rats, 0.8 g/kg dose of 1 hour after injection of malatyonun Royal Jelly 100 mg/kg administered by gavage. Plasma, liver, kidney and brain MDA concentrations of malathion groups were found statistical significance (p |
