Prunus spinosa l. Ekstresinin çeşitli kanser hücre soylarındaki antioksidan ve sitotoksik etkileri

Autor: Karakas N., Okur M.E., Ozturk I., Ayla S., Karadag A.E., Polat D.Ç.
Přispěvatelé: Anadolu Üniversitesi
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Popis: Objective: Blackthorn (Prunus spinosa L. (Rosaceae) is a shrup whose fruits are consumed as food in Turkey. This study was aimed to evaluate antioxidant activity of methanol extract of P. spinosa and its cytotoxic effects on cancer cell lines. Method: Methanol extract of P. spinosa fruit was evaluated for its in vitro cytotoxic activity on multiform (GBM) brain cancer (LN229, U87 and T98G) and pancreas cancer (PANC-1 and AsPC-1) cell lines. Cell viability assays were performed by calculating the percentage of viable cells using a luminescence system, and spectrophotometrically. measuring its antioxidant ABTS and DPPH radical scavenging activities. Differences were considered as statistically significant at p*
Databáze: OpenAIRE