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Aim: The aim of this study is to investigate the effects of iv paracetamol with iv morphine PCA on postoperative morphine consumption in lumbar disc surgery. Materials and Methods: After obtaining the approval of the hospital ethics committee and patient's consents, 67 adult patients, in ASA group's I-III, were randomly divided into two groups. Group M (n=37) received iv morphine Patient Control Analgesia (PCA) postoperatively (bolus dose 1 mg, lock out time 10 min, limited 50 mg 24 hrs-1). At the skin closure, iv paracetamol (1 g infused in 15 min, 8 g 48 hrs-1) was also administered with morphine PCA in Group MP. All the patients with Visual Analogue Scale (VAS) scores over 3 were administered iv morphine in fractioned doses at recovery room (0. minute). The systolic and diastolic arterial pressures, hearth rate, SpO2, breathing rate, PCA demand number, replied demand number and total morphine consumption, sedation scores, VAS scores, presence of nausea and vomiting, itching and patches were recorded at 0., 30., 60. min, 2., 4., 6., 12., 18., 24. and 48. hrs. Fractioned morphine amounts and antiemetic consumption were also recorded. Fractioned morphine amounts, total morphine consumption and sedation scores were found to be lowered in Group MP (p |
